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Asymmetric Synthesis of Amino Acid Derivatives and Total Synthesis of Biologically Active Natural Products

By:

Kesavulu, Gangarajulu

Contributor(s):

Advised by Kesavulu, Gangarajulu

Material type: Text

TextLanguage: en Publication details: Bangalore : Indian Institute of Science, 2024Description: xxii, 370 p. : col. ill. e-Thesis 42.53 MbSubject(s):

DDC classification:

547.7 KES

Online resources:

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Dissertation note: PhD;2024:Organic Chemistry Summary: The thesis describes the development of synthetic method for the synthesis of -amino acid esters, amides, thioesters using Ellman sulfinimines. The procedure developed was further utilized in the synthesis of di and tri peptides without racemization. Further, the use of chiral pool tartaric acid and chiral furyl carbinols in the total synthesis of natural products is described. The targeted natural products include D-lyxo and xylo -Phytospingosines, sphingofungin B, AKML-B, ()-(6S,9R,10R)- Bovidic acid, Towards the synthesis of schulzeine B, and Phomopsolidones.

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Holdings
Item type	Current library	Call number	URL	Status	Date due	Barcode
Thesis	JRD Tata Memorial Library	547.7 KES (Browse shelf(Opens below))	Link to resource	Not for loan		ET00784

Includes bibliographical references

PhD;2024:Organic Chemistry

The thesis describes the development of synthetic method for the synthesis of -amino acid esters, amides, thioesters using Ellman sulfinimines. The procedure developed was further utilized in the synthesis of di and tri peptides without racemization. Further, the use of chiral pool tartaric acid and chiral furyl carbinols in the total synthesis of natural products is described. The targeted natural products include D-lyxo and xylo -Phytospingosines, sphingofungin B, AKML-B, ()-(6S,9R,10R)- Bovidic acid, Towards the synthesis of schulzeine B, and Phomopsolidones.

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