Raman spectroscopy instrumentation and its application in deep tissue imaging

By: Contributor(s): Material type: BookBookLanguage: en. Publication details: Bengaluru IISc 2023Description: 194p. e-Thesis col. ill. ; 29.1 cm * 20.5 cm 7.023MbDissertation: PhD; 2023; Instrumentation and applied physicsSubject(s): DDC classification:
  • 530 VIS
Online resources: Dissertation note: PhD; 2023; Instrumentation and applied physics Summary: Raman spectroscopy is based on inelastic scattering, which gives molecular information. Due to its weak nature, for a long-time Raman spectroscopy was limited to only study of molecular interactions, but with the advancement in technology such as highly compact and stable lasers, high quantum efficiency and low noise detectors and so on, Raman spectroscopy today finds itself in wide applications ranging from study on biological cells to space applications. In the first work we aim to develop a 3D Raman imaging system that can give both chemical and morphological information of the concealed object using Universal Multiple Angle Raman spectroscopy (UMARS). Spatial offset Raman spectroscopy (SORS) is a widely used Raman technique and they can obtain Raman signals upto depth of 5 cm.
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PhD; 2023; Instrumentation and applied physics

Raman spectroscopy is based on inelastic scattering, which gives molecular information. Due to its weak nature, for a long-time Raman spectroscopy was limited to only study of molecular interactions, but with the advancement in technology such as highly compact and stable lasers, high quantum efficiency and low noise detectors and so on, Raman spectroscopy today finds itself in wide applications ranging from study on biological cells to space applications. In the first work we aim to develop a 3D Raman imaging system that can give both chemical and morphological information of the concealed object using Universal Multiple Angle Raman spectroscopy (UMARS). Spatial offset Raman spectroscopy (SORS) is a widely used Raman technique and they can obtain Raman signals upto depth of 5 cm.

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