Vishnu Kumar, R

Raman spectroscopy instrumentation and its application in deep tissue imaging - Bengaluru IISc 2023 - 194p. col. ill. ; 29.1 cm * 20.5 cm e-Thesis 7.023Mb

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PhD; 2023; Instrumentation and applied physics

Raman spectroscopy is based on inelastic scattering, which gives molecular information. Due to its weak nature, for a long-time Raman spectroscopy was limited to only study of molecular interactions, but with the advancement in technology such as highly compact and stable lasers, high quantum efficiency and low noise detectors and so on, Raman spectroscopy today finds itself in wide applications ranging from study on biological cells to space applications. In the first work we aim to develop a 3D Raman imaging system that can give both chemical and morphological information of the concealed object using Universal Multiple Angle Raman spectroscopy (UMARS). Spatial offset Raman spectroscopy (SORS) is a widely used Raman technique and they can obtain Raman signals upto depth of 5 cm.


spontaneous Raman spectroscopy
deep tissue imaging
UMARS

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