TY  - BOOK
AU  - Vaishnav, Madhumati Shrikrishna
AU  - Bhat, Navakanta advised
AU  - Srikanta, Sathyanarayana advised
TI  - Diabetogenesis and albumin molecular modifications newer biological insights and clinical implications
U1  - 616 
PY  - 2022///
CY  - Bangalore
PB  - IISc
KW  - Diabetes
KW  - Albumin
KW  - Molecular Modifications
KW  - Glycation
KW  - Oxidation
N1  - includes bibliographic reference and index; PhD; 2022; Centre for nano science and engineering
N2  - To address the many unmet scientific needs in diabetes care (pathogenesis pathways, earliest diagnosis, efficient monitoring, safer and better therapies and importantly prevention approaches), our research focussed on: (a) diabetogenesis and biomarkers and (b) albumin molecular modifications. Establishment of the “Samatvam – Indian Institute of Science” prospective longitudinal cohort, supported by a well annotated biobank repository and a robust cloud based electronic medical record platform, provided the foundation for this translational scientific endeavour. Initially, the "IISc - PathShodh" electrochemistry technology based multianalyte point of care device (POC: anuPath) for selected diabetes biomarkers (HbA1c, hemoglobin, serum albumin, urine albumin and urine creatinine) was validated by simultaneous comparison with “gold standard” conventional laboratory assays. Health worker-based community implementation of this “lab – on – palm”, confirmed its utility both for “in-clinic” diabetes care and “remote” health monitoring
UR  - https://etd.iisc.ac.in/handle/2005/6122
ER  -