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Translation in the 3'Untranslated Region of Mammalian Transcripts

By:

Kar, Debaleena

Contributor(s):

Advised by Eswarappa, Sandeep M

Material type: Book

BookPublication details: Bangalore: Indian Institute of Science, 2023.Description: ix, 113p.: col. ill. e-Thesis 5.212MbDissertation: PhD;2023;BiochemistrySubject(s):

DDC classification:

572.838 KAR

Online resources:

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Dissertation note: PhD;2023;Biochemistry Summary: Mammalian mRNAs generally have a 5'UTR (untranslated region), a coding DNA sequence, and a 3'UTR. The 3'UTR of mRNA is generally believed to be the untranslated region of the mRNA. However, there are certain instances in which the 3'UTR of mRNA can be translated. Among these are intriguing mechanisms such as Stop Codon Readthrough (SCR) and initiation of translation in a downstream open reading frame (ORF). These two mechanisms are the focus of study in this thesis.

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Holdings
Item type	Current library	Call number	URL	Status	Date due	Barcode
Thesis	JRD Tata Memorial Library	572.88 KAR (Browse shelf(Opens below))	Link to resource	Available		ET00375

Includes bibliographical references

PhD;2023;Biochemistry

Mammalian mRNAs generally have a 5'UTR (untranslated region), a coding DNA sequence, and a 3'UTR. The 3'UTR of mRNA is generally believed to be the untranslated region of the mRNA. However, there are certain instances in which the 3'UTR of mRNA can be translated. Among these are intriguing mechanisms such as Stop Codon Readthrough (SCR) and initiation of translation in a downstream open reading frame (ORF). These two mechanisms are the focus of study in this thesis.

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