N-Heterocyclic carbene-catalyzed synthesis of oxazolones, e-Lactones and N-N Axially chiral molecules (Record no. 429625)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02047nam a22002417a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230818b |||||||| |||| 00| 0 eng d |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | en |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 547 |
| Item number | KUR |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Balanna, Kuruva |
| 245 ## - TITLE STATEMENT | |
| Title | N-Heterocyclic carbene-catalyzed synthesis of oxazolones, e-Lactones and N-N Axially chiral molecules |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Bangalore : |
| Name of publisher, distributor, etc | IISc , |
| Date of publication, distribution, etc | 2023 . |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | v, 192p. |
| Other physical details | col. ill. ; |
| Dimensions | 29.1 cm * 20.5 cm |
| Accompanying material | e-Thesis |
| Size of unit | 16.38Mb |
| 500 ## - GENERAL NOTE | |
| General note | include bibliographic reference and index |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | PhD; 2023; Organic chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | The diverse reactivity of N-heterocyclic carbenes (NHCs) in organocatalysis is due to the possibility of different modes of action. Although NHC-bound enolates and dienolates were well-known, the NHC-bound cross-conjugated aza-trienolates were undisclosed. We have demonstrated the synthesis of pyrrolooxazolones via NHC-bound azatrienolate intermediates. In the same fashion, involvement of chiral alpha-carbon center (proximal reaction centre) in dynamic kinetic resolution (DKR) via NHC-bound enolates were known. However, the gamma, gamma-disubstituted chiral carbon center (remote reaction centre) involving in DKR via NHC-bound dienolates were unknown. We have recently demonstrated the DKR of gamma,gamma-disubstituted indole 2-carboxaldehydes via NHC-Lewis acid cooperative catalysis for the synthesis of tetracyclic epsilon-lactones. Additionally, NHC-catalyzed atroposelective synthesis of C-C and C-N axially chiral molecules were known, and the asymmetric synthesis of axially chiral N-N molecules remains unknown in carbene catalysis. We have demonstrated the N-heterocyclic carbene (NHC)-catalyzed selective amidation reaction leading to the atroposelective synthesis of N-N axially chiral 3-amino quinazolinones. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | N-heterocyclic carbene |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | dynamic kinetic resolution |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | N-N axially chiral molecules |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | pyrrolooxazolones |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Biju, Akkattu T advised |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://etd.iisc.ac.in/handle/2005/6191 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Thesis |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | JRD Tata Memorial Library | JRD Tata Memorial Library | 18/08/2023 | 547 KUR | ET00204 | 18/08/2023 | E-BOOKS |
