Diabetogenesis and albumin molecular modifications newer biological insights and clinical implications (Record no. 428421)

MARC details
000 -LEADER
fixed length control field 01955nam a22002657a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 230615b |||||||| |||| 00| 0 eng d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title en.
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616
Item number MAD
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Vaishnav, Madhumati Shrikrishna
245 ## - TITLE STATEMENT
Title Diabetogenesis and albumin molecular modifications newer biological insights and clinical implications
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Bangalore
Name of publisher, distributor, etc IISc
Date of publication, distribution, etc 2022
300 ## - PHYSICAL DESCRIPTION
Extent xxiv, 296p.
Other physical details col. ill. ;
Dimensions 29.1 cm * 20.5 cm
Accompanying material e-Thesis
Size of unit 16.68Mb
500 ## - GENERAL NOTE
General note includes bibliographic reference and index
502 ## - DISSERTATION NOTE
Dissertation note PhD; 2022; Centre for nano science and engineering
520 ## - SUMMARY, ETC.
Summary, etc To address the many unmet scientific needs in diabetes care (pathogenesis pathways, earliest diagnosis, efficient monitoring, safer and better therapies and importantly prevention approaches), our research focussed on: (a) diabetogenesis and biomarkers and (b) albumin molecular modifications. Establishment of the “Samatvam – Indian Institute of Science” prospective longitudinal cohort, supported by a well annotated biobank repository and a robust cloud based electronic medical record platform, provided the foundation for this translational scientific endeavour. Initially, the "IISc - PathShodh" electrochemistry technology based multianalyte point of care device (POC: anuPath) for selected diabetes biomarkers (HbA1c, hemoglobin, serum albumin, urine albumin and urine creatinine) was validated by simultaneous comparison with “gold standard” conventional laboratory assays. Health worker-based community implementation of this “lab – on – palm”, confirmed its utility both for “in-clinic” diabetes care and “remote” health monitoring.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Diabetes
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Albumin
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Molecular Modifications
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Glycation
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Oxidation
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Bhat, Navakanta advised
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Srikanta, Sathyanarayana advised
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://etd.iisc.ac.in/handle/2005/6122
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis

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