Construction of C-C bonds by photocatalysis via radical addition cascade cyclization (RACC) : (Record no. 427163)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02248nam a22002537a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230323b |||||||| |||| 00| 0 eng d |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | en. |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 547 |
| Item number | SAB |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Manna, Sabyasachi |
| 245 ## - TITLE STATEMENT | |
| Title | Construction of C-C bonds by photocatalysis via radical addition cascade cyclization (RACC) : |
| Remainder of title | Synthesis of heteroatom-containing small molecules |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Bengaluru : |
| Name of publisher, distributor, etc | IISc , |
| Date of publication, distribution, etc | 2022 . |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xxii, 225p. |
| Accompanying material | e-Thesis |
| Other physical details | col. ill. ; |
| Dimensions | 29.1 cm * 20.5 cm |
| Size of unit | 11.49Mb |
| 500 ## - GENERAL NOTE | |
| General note | Include bibliographical references and index |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | PhD; 2022; Organic chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | The thesis presents photocatalytic methods for synthesizing small organic molecules at room temperature. The thesis is divided into four sections. Section A presents the general introduction to the thesis. Section B is presented as a single chapter, which describes an intramolecular ipso-arylative cyclization of aryl alkynoate with tricarbonyl compounds under photocatalytic conditions via radical addition cascade cyclization (RACC). The methodology could be extended to the arylpropiolamides and arylthioates as well. Section C is presented in two Chapters, Chapters 3 and 4. Chapter 3 describes a visible light-mediated difunctionalization of activated alkynes to form coumarin and spirolactones. The coumarins and spirolactones could be formed selectively by tuning the substituent present in the aryl alkynoate. The spirolactones synthesized in this method can be transformed into complex spirocyclic structures under a separate visible light-mediated reaction. Chapter 4 describes a visible light-mediated radical addition cascade cyclization (RACC) between maleimides and phenethylboronic acids to access fused tetrahydro-1H-benzo[e]isoindole-1,3(2H)-diones. The last section is presented as Chapter 5, which deals with a photocatalytic approach to the direct acylation of electron-deficient heteroarenes. The methodology could be used to synthesize biologically active small molecules. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Photocatalysis |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Boronic acid |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Maleimide |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Alkynoate |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Radical addition |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Prabhu, K R advised |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://etd.iisc.ac.in/handle/2005/6050 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Thesis |
No items available.
