Asymmetric Synthesis of Amino Acid Derivatives and Total Synthesis of Biologically Active Natural Products
Material type:
TextLanguage: en Publication details: Bangalore : Indian Institute of Science, 2024Description: xxii, 370 p. : col. ill. e-Thesis 42.53 MbSubject(s): DDC classification: - 547.7 KES
| Item type | Current library | Call number | URL | Status | Date due | Barcode | |
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Thesis
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JRD Tata Memorial Library | 547.7 KES (Browse shelf(Opens below)) | Link to resource | Not for loan | ET00784 |
Includes bibliographical references
PhD;2024:Organic Chemistry
The thesis describes the development of synthetic method for the synthesis of -amino acid esters, amides, thioesters using Ellman sulfinimines. The procedure developed was further utilized in the synthesis of di and tri peptides without racemization. Further, the use of chiral pool tartaric acid and chiral furyl carbinols in the total synthesis of natural products is described. The targeted natural products include D-lyxo and xylo -Phytospingosines, sphingofungin B, AKML-B, ()-(6S,9R,10R)- Bovidic acid, Towards the synthesis of schulzeine B, and Phomopsolidones.
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